Mitochondrial dysfunctions and neurodegenerative diseases: a mini-review

Mitochondrial dysfunction is estimated to be the primary reason involved in different types of neurodegenerative disorders as mitochondria suggested important production reactive oxygen species. Recently, several evidences have emerged out for impaired mitochondrial structures and functions viz. shape, size, fission-fusion, distribution, movement etc. diseases especially with Alzheimer’s disease, Parkinson’s disease Huntington’s disease. Therefore, apart from looking on whole, a detailed understanding functioning their role degeneration would pave new options therapy age-related diseases.